The 8th house describes the nature of your immune system. Everyone’s immune system is different! The sign on the cusp, the planets in them and the nature of the traditional ruler (and the modern ruler) tell you about the nature of your immune system, especially any quirks. If you have a sign with a traditional and a modern ruler, like Scorpio, Aquarius, and Pisces, you may have a more nuanced immune system.
To that end, the 8th house dealing with healing. The 6th house deals with hygiene and medicine, but the process of healing is an 8th house thing.
Modern rulerships or traditional rulerships? Traditional rulerships are best for anything that is more personal, like a medical chart or horary, whereas anything that deals with the world at large can have modern rulerships. However, for a natal chart, try taking both into account and blending the interpretations.
Gender bending fabulousness? Check for relationships between Uranus and Venus and Mars.
People with a lot of trines in their chart seem to go through life effortlessly. Unfortunately, they also tend to lack ambition, since they have always gotten what they wanted and people seem to just give it to them.
People with a lot of separate conjunctions in their chart, though rare, tend to not shine without a lot of effort, because each planet is always tied to the expression of another planet. This is someone who has probably not had to work hard in their youth and as an adult, tends to second-guess themselves. On the other hand, if they become confident as adults, they can be masters of synchronicity.